NIH-funded research R01 grant

CAREZ: Bringing HIV and NCD Care Together in Zambia

Official title: Community-TASKPEN Approach for NCD Multimorbidity Response and Engagement of PLHIV in Zambia" ('CAREZ') study

Funded at Centre for Infectious Disease Research · NIH-11328299 · Data updated 2026-11-12

A patient-focused program uses community health workers and mobile teams to help people living with HIV in Zambia better manage heart disease and other chronic conditions using a simple, easy-to-follow care package.

More Multimorbidity research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCentre for Infectious Disease Research
NIH-funded
Lab location1 site (Lusaka, Zambia)
Project startAugust 20, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$548,242
NIH project number1R01TW013248-01
Project IDNIH-11328299 on NIH RePORTER

Who could benefit from this research

Could help

Adults living with HIV in Zambia who also have or are at risk for cardiometabolic non-communicable diseases and can participate in community-based care delivery.

Less likely to help

Patients without HIV or without cardiometabolic NCDs or those unable to engage with community-based care teams may see limited or no benefits.

What this research studies

This project adapts a practical care package for HIV patients with multiple chronic conditions and brings it to communities in Zambia through mobile care teams led by community health workers. It uses easy treatment guides, simple point-of-care tests, and multi-month medication dispensing to help people manage HIV and cardiometabolic diseases together. The care model leverages mobile health technology to screen, monitor, and support patients in local health structures, aiming to improve treatment control and quality of life. The study builds on an evidence-based approach and tests how well this integrated CAREZ model works in real-world settings for people living with HIV.

Why it matters

Potential benefit: If successful, patients could experience better control of HIV and other chronic conditions, reduced hospital visits, and easier access to integrated care in their communities.

How similar studies have gone: Previous work shows promise for task-shifting and community-based NCD management, with potential for improved access and outcomes in similar settings.

Where this research is happening

  • Centre for Infectious Disease Research
    Lusaka, Zambia
    Active

Researchers

  • Principal investigator: Bosomprah, Samuel — Centre for Infectious Disease Research
  • Study coordinator: Bosomprah, Samuel

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.