Carbapenemase-Producing Enterobacterales in Companion Animals: A Five-Year Update
Official title: Prevalence of Carbapenemase-Producing Enterobacterales in Companion Animals: A Five-Year Update Study.
Funded at University of Pennsylvania · NIH-11527030 · Data updated 2026-11-12
This project follows dogs and cats over five years to see how common and diverse carbapenem-resistant bacteria are in pets and how they might connect to human health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $65,000 |
| NIH project number | 1U18FD008915-01 |
| Project ID | NIH-11527030 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal participants are dogs or cats seen at participating veterinary laboratories or clinics during the study period.
✕Less likely to help
Pets not enrolled in the sampling or from non-participating sites may not contribute to the findings.
What this research studies
Pet animals, especially dogs and cats, may carry dangerous bacteria that resist last-resort antibiotics. The study will sample feces from companion animals across multiple labs over five years to track how often these bacteria occur and what kinds of resistance genes they carry. By linking findings to known human-related lineages, researchers hope to understand transmission at the human–animal interface. The work builds on a previous national survey and aims to show trends in prevalence and diversity over time.
Why it matters
Potential benefit: If successful, the findings could inform veterinarians and clinicians about evolving resistance in pets and guide actions to protect both animal and human health.
How similar studies have gone: A prior multicenter national survey demonstrated detectable CP-CRE in companion animals, supporting the value of longitudinal follow-up.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Cole, Stephen Douglas — University of Pennsylvania
- Study coordinator: Cole, Stephen Douglas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.