Cancer Metabolism Core for Pancreatic Cancer Research and Therapy Resistance
Official title: Cancer Metabolism Core
Funded at University of Oklahoma Hlth Sciences Ctr · NIH-11421834 · Data updated 2026-11-12
A centralized core lab helps study how metabolism and signaling changes drive therapy resistance in pancreatic cancer, supporting multiple projects.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Oklahoma Hlth Sciences Ctr NIH-funded |
| Lab location | 1 site (Oklahoma City, United States) |
| Project start | September 20, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $77,149 |
| NIH project number | 5U54CA274329-05 |
| Project ID | NIH-11421834 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable here; this is a core research resource supporting studies that may include patient-derived samples.
✕Less likely to help
Direct patient benefit is not guaranteed from participating in core activities; this is primarily a service for researchers.
What this research studies
This program provides specialized metabolomics, data analysis, and metabolic screening services to pancreatic cancer researchers. It uses advanced techniques like polar metabolomics, lipidomics, and stable isotope tracing to map how cancer cells rewire their metabolism. The core collaborates across three projects to ensure data quality, experimental design, and translation-ready insights from cell lines, organoids, and tissue samples.
Why it matters
Potential benefit: If successful, patients with pancreatic cancer could benefit from faster, more precise understanding of therapy resistance and new metabolic targets.
How similar studies have gone: Metabolic profiling and isotope tracing have shown promise in revealing cancer vulnerabilities in prior work.
Where this research is happening
-
University of Oklahoma Hlth Sciences Ctr
Oklahoma City, United States Active
Researchers
- Principal investigator: Singh, Pankaj Kumar — University of Oklahoma Hlth Sciences Ctr
- Study coordinator: Singh, Pankaj Kumar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.