Caenorhabditis Intervention Testing Program: Interventions that may extend healthy aging
Official title: Caenorhabditis Intervention Testing Program: Interventions That Modulate Health, Longevity and Aging Hallmarks
Funded at Rutgers, the State Univ of N.j. · NIH-11378177 · Data updated 2026-11-12
A research grant that tests potential anti-aging interventions in a worm model to identify approaches that could help people live longer and healthier lives as they age.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rutgers, the State Univ of N.j. NIH-funded |
| Lab location | 1 site (Piscataway, United States) |
| Project start | August 15, 2013 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $591,330 |
| NIH project number | 5U01AG045864-13 |
| Project ID | NIH-11378177 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not a patient-facing trial; results could influence future aging-targeted therapies for older adults.
✕Less likely to help
Direct participation by patients is not involved in this grant.
What this research studies
This project continues a collaboration among three labs to test drug-like interventions in the tiny worm Caenorhabditis elegans, aiming to find treatments that promote healthy aging across diverse genetic backgrounds. The work uses nematodes to screen how certain compounds may extend healthy lifespan and delay age-related decline. By including natural variants of Caenorhabditis, the study seeks results that are more likely to translate to diverse human populations. Findings could point toward preclinical ideas for extending healthspan in people as they age.
Why it matters
Potential benefit: If successful, the research could inform strategies that promote healthier aging in humans.
How similar studies have gone: Aging research using Caenorhabditis models has shown promise in identifying interventions that affect longevity and healthspan in multiple studies.
Where this research is happening
-
Rutgers, the State Univ of N.j.
Piscataway, United States Active
Researchers
- Principal investigator: Driscoll, Monica a. — Rutgers, the State Univ of N.j.
- Study coordinator: Driscoll, Monica a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.