NIH-funded research U01 cooperative agreement

Caenorhabditis Intervention Testing Program: Interventions that may extend healthy aging

Official title: Caenorhabditis Intervention Testing Program: Interventions That Modulate Health, Longevity and Aging Hallmarks

Funded at Rutgers, the State Univ of N.j. · NIH-11378177 · Data updated 2026-11-12

A research grant that tests potential anti-aging interventions in a worm model to identify approaches that could help people live longer and healthier lives as they age.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionRutgers, the State Univ of N.j.
NIH-funded
Lab location1 site (Piscataway, United States)
Project startAugust 15, 2013
Project endJuly 31, 2027
Funding year2026
Award (this year)$591,330
NIH project number5U01AG045864-13
Project IDNIH-11378177 on NIH RePORTER

Who could benefit from this research

Could help

Not a patient-facing trial; results could influence future aging-targeted therapies for older adults.

Less likely to help

Direct participation by patients is not involved in this grant.

What this research studies

This project continues a collaboration among three labs to test drug-like interventions in the tiny worm Caenorhabditis elegans, aiming to find treatments that promote healthy aging across diverse genetic backgrounds. The work uses nematodes to screen how certain compounds may extend healthy lifespan and delay age-related decline. By including natural variants of Caenorhabditis, the study seeks results that are more likely to translate to diverse human populations. Findings could point toward preclinical ideas for extending healthspan in people as they age.

Why it matters

Potential benefit: If successful, the research could inform strategies that promote healthier aging in humans.

How similar studies have gone: Aging research using Caenorhabditis models has shown promise in identifying interventions that affect longevity and healthspan in multiple studies.

Where this research is happening

  • Rutgers, the State Univ of N.j.
    Piscataway, United States
    Active

Researchers

  • Principal investigator: Driscoll, Monica a. — Rutgers, the State Univ of N.j.
  • Study coordinator: Driscoll, Monica a.

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.