Bringing people back to HIV care and keeping them on treatment in Zambia

Sequential Strategies to Reach and Reengage Individuals after Lapses from HIV Care in Zambia

NIH-funded research Washington University · NIH-11166323

This project tests whether personalized outreach navigators plus community medication delivery can help people in Zambia who stopped HIV care return and stay on antiretroviral treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWashington University NIH-funded
Lab location1 site (Saint Louis, United States)
Project IDNIH-11166323 on NIH RePORTER

What this research studies

If you have missed HIV treatment visits in Zambia, this project focuses on getting you back into care and preventing future lapses. It compares and combines two approaches: trained navigators who tailor outreach, care coordination, and psychosocial support, and delivering HIV medicines in the community to make access easier. Participants who return to care will be followed to see which timing and combinations of services best prevent repeat lapses. The team will use person-centered outreach and community-based medication delivery across study sites in Zambia to find practical ways to keep people engaged in treatment.

Who could benefit from this research

Good fit: Ideal candidates are people in Zambia living with HIV who have missed appointments or stopped antiretroviral therapy and are willing to be contacted for outreach and community medication delivery.

Not a fit: People who are already consistently in HIV care and virally suppressed, or those living outside the study communities in Zambia, are unlikely to receive direct benefit from participation.

Why it matters

Potential benefit: If successful, this could help more people resume HIV treatment, keep viral loads suppressed, and reduce hospitalizations and deaths.

How similar studies have performed: Navigation and community-based medication delivery have improved outcomes for new or stable ART patients in earlier work, but combining and sequencing these approaches for people with treatment lapses is relatively untested.

Where this research is happening

Saint Louis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusChronic Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.