NIH-funded research R01 grant

Brief Behavioral Activation to help older cancer survivors feel better

Official title: A Randomized Controlled Trial of Brief Behavioral Activation for Older Adult Cancer Survivors

Funded at Sloan-Kettering Inst Can Research · NIH-11375557 · Data updated 2026-11-12

A study will test a short behavioral therapy to help adults aged 65 and older who have survived cancer manage depression and stay engaged with care.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research
NIH-funded
Lab location1 site (New York, United States)
Project startJune 1, 2026
Project endMay 31, 2031
Funding year2026
Award (this year)$731,503
NIH project number1R01CA309492-01A1
Project IDNIH-11375557 on NIH RePORTER

Who could benefit from this research

Could help

Adults aged 65 and older who have completed cancer treatment and are experiencing depressive symptoms or low mood.

Less likely to help

Older adults without depressive symptoms or those unable to participate in behavioral activation exercises may not benefit.

What this research studies

This project tests a brief, practical therapy designed for older adults who have finished cancer treatment and are experiencing depression or low mood. The therapy focuses on activating daily routines and enjoyable activities to improve mood and health behaviors. It uses an R01-funded, randomized design to compare the brief activation approach with usual care over a set period. If successful, it could offer a scalable option that fits the needs and limitations of older survivors who may face mobility or fatigue challenges.

Why it matters

Potential benefit: If successful, participants could feel less depressed and more likely to engage in follow-up cancer care and healthy behaviors.

How similar studies have gone: Behavioral activation has shown promise in adults and may be particularly helpful for older cancer survivors, though results in this exact population are being tested.

Where this research is happening

  • Sloan-Kettering Inst Can Research
    New York, United States
    Active

Researchers

  • Principal investigator: Saracino, Rebecca — Sloan-Kettering Inst Can Research
  • Study coordinator: Saracino, Rebecca

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.