Brain Training for Alzheimer's Disease Memory and Thinking
Official title: Phase IIB Plasticity-based Adaptive Cognitive Remediation for Alzheimers Disease
Funded at Posit Science Corporation · NIH-11019846 · Data updated 2026-11-12
This project explores how a special brain training program might help people with Alzheimer's disease maintain their memory and thinking skills over a long time.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Posit Science Corporation NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 30, 2014 |
| Project end | January 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $826,900 |
| NIH project number | 5R44AG047722-09 |
| Project ID | NIH-11019846 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are adults aged 21 and older who have been diagnosed with Alzheimer's disease or related dementias and are able to participate in cognitive training.
✕Less likely to help
Patients who are unable to actively engage with cognitive training activities or those with very advanced dementia may not receive benefit from this specific program.
What this research studies
This project is looking at a specific brain training program called PACR-AD, designed to help individuals with Alzheimer's disease. We want to understand if the positive effects of this training can last for five years after the initial program is completed. We are also testing if a short 'booster' training session, given five years later, can further improve or maintain these benefits. Our aim is to find the best possible training schedule to help sustain and potentially enhance the program's positive impact on memory and thinking abilities. This work could lead to an evidence-based tool for managing age-related cognitive decline.
Why it matters
Potential benefit: If successful, this program could offer a new, non-drug approach to help people with Alzheimer's disease maintain their cognitive abilities and quality of life for a longer period.
How similar studies have gone: Previous research has shown some promise with cognitive training approaches, and this project aims to build on those findings by examining long-term effects and booster training.
Where this research is happening
-
Posit Science Corporation
San Francisco, United States Active
Researchers
- Principal investigator: Lee, Hyun Kyu — Posit Science Corporation
- Study coordinator: Lee, Hyun Kyu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.