Brain Training for Alzheimer's Disease Memory and Thinking

Phase IIB Plasticity-based Adaptive Cognitive Remediation for Alzheimers Disease

NIH-funded research Posit Science Corporation · NIH-11019846

This project explores how a special brain training program might help people with Alzheimer's disease maintain their memory and thinking skills over a long time.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionPosit Science Corporation NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11019846 on NIH RePORTER

What this research studies

This project is looking at a specific brain training program called PACR-AD, designed to help individuals with Alzheimer's disease. We want to understand if the positive effects of this training can last for five years after the initial program is completed. We are also testing if a short 'booster' training session, given five years later, can further improve or maintain these benefits. Our aim is to find the best possible training schedule to help sustain and potentially enhance the program's positive impact on memory and thinking abilities. This work could lead to an evidence-based tool for managing age-related cognitive decline.

Who could benefit from this research

Good fit: Ideal candidates are adults aged 21 and older who have been diagnosed with Alzheimer's disease or related dementias and are able to participate in cognitive training.

Not a fit: Patients who are unable to actively engage with cognitive training activities or those with very advanced dementia may not receive benefit from this specific program.

Why it matters

Potential benefit: If successful, this program could offer a new, non-drug approach to help people with Alzheimer's disease maintain their cognitive abilities and quality of life for a longer period.

How similar studies have performed: Previous research has shown some promise with cognitive training approaches, and this project aims to build on those findings by examining long-term effects and booster training.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.