Biochemistry of membrane proteins that process lipids and cannabinoids
Official title: Biochemistry of membrane proteins involved in lipid and cannabinoid metabolism
Funded at Georgia Institute of Technology · NIH-11380770 · Data updated 2026-11-12
This NIH grant funds basic biology research to understand how membrane proteins metabolize lipids and cannabinoid-like compounds, with potential implications for disease biology.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Georgia Institute of Technology NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | August 1, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $371,909 |
| NIH project number | 5R35GM152121-03 |
| Project ID | NIH-11380770 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not a clinical trial; information may inform future therapies for people with lipid metabolism disorders or cannabinoid-related conditions.
✕Less likely to help
No immediate clinical benefit to patients; this is foundational science.
What this research studies
The project seeks to uncover the fundamental chemistry and mechanisms by which membrane proteins process lipids and lipid-like drugs such as cannabinoids. Scientists will use a combination of chemical synthesis, proteomics, nanodiscs, lipidomics, spectroscopy, molecular dynamics, imaging, and cell culture to map how these proteins work and what metabolites they produce. The goal is to connect these basic mechanisms to how lipids influence immune signaling and disease processes, laying groundwork for future therapies. This work is conducted in a university lab with a track record of NIGMS-funded research and published findings on lipid metabolism. Participants may see advances that eventually translate into treatments for lipid-related diseases or immunomodulation.
Why it matters
Potential benefit: If successful, the research could inform new strategies to treat diseases linked to lipid metabolism and cannabinoid-related pathways.
How similar studies have gone: Previous studies in lipid metabolism and CYP-mediated pathways have yielded important insights, supporting the potential value of this approach.
Where this research is happening
-
Georgia Institute of Technology
Atlanta, United States Active
Researchers
- Principal investigator: Das, Aditi — Georgia Institute of Technology
- Study coordinator: Das, Aditi
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.