Better planning for prevention and treatment across multiple myeloma stages
Comparative modeling of multiple myeloma across myeloma continuum: prevention, treatment, and health drivers
This project uses computer models to compare prevention and treatment options for people at risk for or living with multiple myeloma.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-11192289 on NIH RePORTER |
What this research studies
From my perspective as someone affected by multiple myeloma, this program uses computer-based population models and existing clinical and registry data to compare prevention, screening, and treatment strategies across disease stages including MGUS and smoldering myeloma. Two independent modeling teams will run scenarios coordinated by a central coordinating center to estimate effects on survival, harms, and costs. The work will look at introducing new therapies and the possible de-implementation of older approaches to show trade-offs. The results are intended to help clinicians and policymakers choose strategies that could benefit people like me.
Who could benefit from this research
Good fit: Adults (21+) with multiple myeloma, smoldering myeloma, MGUS, or those concerned about MM are the populations represented in the models.
Not a fit: Because this is modeling work rather than a treatment trial, patients will not receive direct medical care or immediate clinical benefit by participating in the project itself.
Why it matters
Potential benefit: Could identify which prevention and treatment approaches are likely to improve survival, reduce harms, and lower costs for people with or at risk for multiple myeloma.
How similar studies have performed: Modeling networks like CISNET have informed breast and colorectal cancer policy successfully, but applying this comparative modeling approach to multiple myeloma is new.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Chang, Su-Hsin — Washington University
- Study coordinator: Chang, Su-Hsin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.