Automatic clinic water chlorination to protect newborns and mothers

Multi-component chlorination intervention to reduce neonatal infections in rural health facilities

NIH-funded research University of California Berkeley · NIH-11110398

This project introduces an automatic, low-cost water chlorination system in rural Kenyan clinics to help protect newborns and their mothers from infections.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Berkeley NIH-funded
Lab location1 site (Berkeley, United States)
Project IDNIH-11110398 on NIH RePORTER

What this research studies

If you give birth at a participating rural clinic in Kenya, some clinics will get a Venturi in-line chlorination device plus an electrochlorinator that makes chlorine from water and salt. The devices dose chlorine automatically and are designed to provide safe water and disinfect hands and high-touch surfaces without complex maintenance or electricity. Researchers will run a cluster-randomized trial across 30 clinics, testing water, surfaces, and healthcare worker hands for harmful and antibiotic-resistant bacteria. They will also follow mothers and newborns after birth to see whether infections and related health problems are reduced.

Who could benefit from this research

Good fit: Ideal participants are mothers and newborns (especially babies 0–4 weeks old) who receive care at the participating rural Kenyan health facilities.

Not a fit: Patients who do not visit the participating clinics, whose infections are unrelated to clinic water or surfaces, or who seek care at better-resourced hospitals may not receive direct benefit from this intervention.

Why it matters

Potential benefit: If successful, this approach could reduce newborn and maternal infections and lower the risk of antibiotic-resistant infections by keeping clinic water and surfaces cleaner.

How similar studies have performed: Chlorination has been shown to reduce waterborne germs and illness in other settings, but using an automatic in-line system paired with on-site chlorine production in rural health facilities is a newer approach with limited prior trials.

Where this research is happening

Berkeley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Bacterial Infections
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.