NIH-funded research Sbir 2 grant

At-home computer-based cognitive tests to build norms for aging and dementia across diverse US populations

Official title: At-home computerized assessment of normal cognitive aging and age-related cognitive decline in older African Americans, Hispanics, and rural non-Hispanic whites

Funded at Neurobehavioral Systems, INC. · NIH-11370594 · Data updated 2026-11-12

A new at-home, AI-assisted cognitive test battery will create population-based norms for aging and Alzheimer’s-related cognitive changes using diverse groups.

More Aging research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNeurobehavioral Systems, INC.
NIH-funded
Lab location1 site (Berkeley, UNITED STATES)
Project startSeptember 30, 2022
Project endMay 31, 2027
Funding year2026
Award (this year)$832,200
NIH project number5R44AG080951-04
Project IDNIH-11370594 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (60–89 years) who identify as African American, Asian American, English-speaking Hispanic, or Spanish-speaking Hispanic and are able to complete computer-based assessments at home or in a clinic.

Less likely to help

Individuals outside the specified demographic groups or those unable to use telemedicine or a computer-based test may not benefit.

What this research studies

This project will collect longitudinal data from 4 demographic groups (African Americans, Asian Americans, English-speaking Hispanics, and Spanish-speaking Hispanics) aged 60–89 to establish representative cognitive norms. It uses the California Cognitive Assessment Battery (CCAB), a 34-test computerized platform that can be done in a clinic or at home via telemedicine, aided by AI voice and speech recognition. Data will be combined with existing norms to better reflect the diversity of the US population and improve accuracy in diagnosing cognitive decline. Phase I focuses on enrollment and translation optimization, while Phase II expands testing and validation in real-world settings.

Why it matters

Potential benefit: If successful, clinicians will have more accurate, representative tools to detect and monitor Alzheimer's-related cognitive changes in diverse populations.

How similar studies have gone: Previous work with CCAB and similar digital neuropsychological tools has shown promise in rapid, scalable data collection and normative development.

Where this research is happening

  • Neurobehavioral Systems, INC.
    Berkeley, United States
    Active

Researchers

  • Principal investigator: Woods, David L — Neurobehavioral Systems, INC.
  • Study coordinator: Woods, David L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.