Assessing vaginal health after pelvic radiotherapy using advanced ultrasound imaging
Clinical assessment of radiotherapy-induced vaginal toxicity with multiparametric ultrasound imaging
['FUNDING_R21'] · SLOAN-KETTERING INST CAN RESEARCH · NIH-10872807
This study is looking at how pelvic radiotherapy affects vaginal health in women being treated for certain cancers, and it aims to create a new ultrasound technique to better understand any changes in vaginal tissue before and after treatment, helping to improve care for patients experiencing issues like pain or sexual problems.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | SLOAN-KETTERING INST CAN RESEARCH (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10872807 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of pelvic radiotherapy on vaginal health in women undergoing treatment for gynecological and anorectal cancers. It aims to develop a new imaging technique using multiparametric ultrasound to objectively measure vaginal tissue health before and after treatment. By utilizing advanced imaging methods, the study seeks to provide more accurate assessments of radiation-induced vaginal toxicity, which can lead to complications such as pain and sexual dysfunction. The research will involve a clinical study with endometrial cancer patients receiving intravaginal brachytherapy to correlate ultrasound findings with traditional clinical assessments.
Who could benefit from this research
Good fit: Ideal candidates for this research are women diagnosed with high-intermediate risk endometrial cancer who are undergoing post-operative intravaginal brachytherapy.
Not a fit: Patients who are not undergoing pelvic radiotherapy or those with other types of cancer unrelated to the study focus may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and management of vaginal toxicity in cancer patients, enhancing their quality of life.
How similar studies have performed: While the use of ultrasound imaging in this context is innovative, similar approaches in other areas of cancer treatment have shown promise in improving patient outcomes.
Where this research is happening
NEW YORK, UNITED STATES
- SLOAN-KETTERING INST CAN RESEARCH — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BURGESS, MARK THOMAS — SLOAN-KETTERING INST CAN RESEARCH
- Study coordinator: BURGESS, MARK THOMAS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anal Cancer, Anal Cancers