Assessing brain oxygen metabolism using MRI technology
MRI-Based Regional Assessment of Cerebral Metabolism Via 3D Quantitative BOLD
This study is looking at a new way to check how well your brain uses oxygen by using MRI scans, which could help doctors better understand brain health and conditions without needing any invasive tests.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10578782 on NIH RePORTER |
What this research studies
This research investigates how to measure brain oxygen metabolism noninvasively using MRI techniques. It focuses on quantifying two key factors: cerebral blood flow and oxygen extraction fraction, which together determine the rate of oxygen consumption in the brain. By developing advanced MRI methods, the study aims to improve the understanding of various neurological disorders and normal brain function. Patients may benefit from more accurate assessments of their brain health without the need for invasive procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with neurological disorders or those undergoing evaluation for brain health.
Not a fit: Patients with stable neurological conditions that do not require further assessment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools for neurological disorders, enhancing patient care and treatment outcomes.
How similar studies have performed: Previous research has shown promise in using MRI techniques for brain metabolism assessment, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Wehrli, Felix W — University of Pennsylvania
- Study coordinator: Wehrli, Felix W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.