Arizona Cancer Prevention Network

University of Arizona Cancer Prevention Clinical Trials Network

NIH-funded research University of Arizona · NIH-11222602

This program tests early treatments and preventive approaches to help stop cancers of the skin, gastrointestinal tract, lung and upper airways, breast and gynecologic organs, and prostate in people at higher risk.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Arizona NIH-funded
Lab location1 site (Tucson, United States)
Project IDNIH-11222602 on NIH RePORTER

What this research studies

The University of Arizona leads a network of sites running early-phase clinical trials of medicines, topical immune treatments, vaccines, and microbiome-targeting approaches aimed at preventing cancer before it starts. Trials focus on five organ groups and enroll people at increased risk, such as organ transplant recipients, smokers, and other defined community groups. Researchers collect clinical information and biological samples and use biomarkers and molecular pathway data to see whether interventions reduce early signs of cancer. The multi-center network connects participants to cutting-edge preventive options through partner sites across the country.

Who could benefit from this research

Good fit: Ideal candidates are people at elevated risk for the targeted cancers—for example smokers, organ transplant recipients, or those with early abnormal findings—who can attend a participating center.

Not a fit: People without risk factors for the included cancer types or those unable to travel to network sites may not receive direct benefit from these trials.

Why it matters

Potential benefit: If successful, this work could lower the chance of developing certain cancers or allow cancers to be intercepted earlier when treatment is simpler.

How similar studies have performed: Previous network-led prevention efforts have influenced HPV vaccine guidance and tested drugs like low-dose apalutamide, showing that some approaches can change practice, while several immune- and microbiome-based strategies remain novel and early-stage.

Where this research is happening

Tucson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced CancerCancer BurdenCancer Causing Agents
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.