ARISEN: Advancing research on autoimmune brain diseases and neuroinflammation
Official title: ARISEN (Autoimmunity, Rasmussen’s, Inflammation & Status Epilepticus research Network)
Funded at Emory University · NIH-11417463 · Data updated 2026-11-12
This grant supports a Career Enhancement Core to train the next generation of clinician-scientists studying autoimmune brain diseases like autoimmune encephalitis, Rasmussen’s syndrome, and NORSE, with a focus on pediatric cases.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | September 15, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $134,817 |
| NIH project number | 5U54HD122209-02 |
| Project ID | NIH-11417463 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable (research training program); however, outcomes may ultimately benefit patients through more trained clinicians and researchers.
✕Less likely to help
This grant focuses on training researchers and does not enroll patients directly.
What this research studies
ARISEN’s Career Enhancement Core aims to grow a diverse, multidisciplinary community of researchers who will work on rare neuroinflammatory disorders. The program will leverage existing infrastructure at Emory to mentor and support investigators new to this disease area, tracking progress through publications, collaborations, and funding. Participants will receive structured mentorship, career development resources, and opportunities to collaborate across centers to accelerate translational insights for affected children and families.
Why it matters
Potential benefit: If successful, the program could accelerate the development of physician-scientists who advance treatments and care for children with autoimmune brain inflammation.
How similar studies have gone: Other rare-disease mentorship and career-development programs have improved researcher training and collaboration, though this area remains specialized.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Murray, Kristy — Emory University
- Study coordinator: Murray, Kristy
Related research
Other NIH-funded projects on the same topics.
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Microglia Help Finish Seizures and Heal the Brain
Scientists are studying how brain immune cells (microglia) help end severe seizures and repair brain damage, with potential new ideas for people who have had status epilepticus.
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ARISEN Network pilot funding to advance autoimmune encephalitis and NORSE care
A pilot grants program within the ARISEN network offers small funding to researchers to speed up clinical trials and improve management and treatment of autoimmune encephalitis, Rasmussen syndrome, and NORSE.
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ARISEN Network: Better Diagnosis and Treatment for Autoimmune Brain Inflammation in Children
A large team at Emory is building ways to diagnose autoimmune brain inflammation in kids earlier and tailor treatments to improve outcomes.
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ARISEN Network: Patient-centered outcomes in autoimmune brain inflammation and status epilepticus
A nationwide registry study from Emory will collect patient- and caregiver-reported outcomes to understand how neuroinflammatory brain diseases affect people and what helps them most.
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ARISEN: A regional network to understand autoimmune brain diseases in kids
A national, multi-center effort follows children with autoimmune brain diseases to better understand how their condition progresses and how it affects thinking and everyday life.
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ARISEN aims to improve outcomes for autoimmune brain diseases in children and adults
A network-led effort to better understand and treat autoimmune brain conditions like autoimmune encephalitis, Rasmussen syndrome, and NORSE through a multi-center registry and coordinated care approaches.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.