Analyzing viruses in the gut related to inflammatory bowel disease
Computational and Experimental Resources for Virome Analysis in Inflammatory Bowel Disease (CERVAID)
This study is looking at how the viruses in our gut might affect conditions like inflammatory bowel disease (IBD) and AIDS, and it’s for people interested in understanding how these viruses can impact their health over time.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10652541 on NIH RePORTER |
What this research studies
This research investigates the role of the virome, which includes viruses in the gut, in relation to inflammatory bowel disease (IBD) and AIDS. It aims to understand how changes in the virome may contribute to these diseases by studying well-defined human cohorts over time. The research will also address the challenge of 'dark matter' in virome studies, which refers to unclassified viral sequences that may hold important information. By developing better experimental systems to manipulate and study these viruses, the research seeks to uncover significant associations between the virome and health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with inflammatory bowel disease or AIDS.
Not a fit: Patients with conditions unrelated to the virome or those who are not adults may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new insights and potential treatments for patients with inflammatory bowel disease and related conditions.
How similar studies have performed: Other research has shown promising results in understanding the microbiome's role in health, but the specific focus on the virome in IBD is relatively novel.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Wang, David — Washington University
- Study coordinator: Wang, David
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.