Analyzing tissue samples to understand autoimmune diseases
Official title: Integrative analysis of high dimensional tissue molecular data to define key biological systems in autoimmune diseases (SBC)
Funded at Brigham and Women's Hospital · NIH-11017785 · Data updated 2026-11-12
This study is looking at how different cells and molecules in your body work together in autoimmune diseases like rheumatoid arthritis and lupus, using samples from patients to help find better ways to treat these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 18, 2022 |
| Project end | December 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $600,000 |
| NIH project number | 5UC2AR081023-04 |
| Project ID | NIH-11017785 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with autoimmune diseases such as rheumatoid arthritis, systemic lupus erythematosus, or related conditions.
✕Less likely to help
Patients with non-autoimmune conditions or those not diagnosed with any autoimmune diseases may not benefit from this research.
What this research studies
This research investigates the biological systems involved in autoimmune diseases by analyzing high-dimensional molecular and cellular data from patient tissue and blood samples. The project aims to identify key cell states, pathways, and molecular components that contribute to tissue inflammation and damage in conditions such as rheumatoid arthritis and systemic lupus erythematosus. By employing advanced analytical methods, the research seeks to uncover how different cell types interact and function in the context of these diseases, ultimately leading to a better understanding of their mechanisms. Patients' samples will be crucial for generating comprehensive data that can inform future treatments.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and targeted therapies for patients with autoimmune diseases.
How similar studies have gone: Previous research using similar high-dimensional analysis approaches has shown promise in understanding autoimmune diseases, indicating that this methodology is both relevant and potentially impactful.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Raychaudhuri, Soumya — Brigham and Women's Hospital
- Study coordinator: Raychaudhuri, Soumya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.