Analyzing the molecules released by individual cells to understand immune responses
NanoSMS: single molecule secretome analysis for non-destructive cellular fingerprinting
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA RIVERSIDE · NIH-10912709
This study is testing a new technology that helps scientists see how individual immune cells work and communicate, especially in patients with autoimmune disorders, to better understand their responses and potentially create better treatments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA RIVERSIDE (nih funded) |
| Locations | 1 site (RIVERSIDE, UNITED STATES) |
| Trial ID | NIH-10912709 on ClinicalTrials.gov |
What this research studies
This research focuses on developing a new technology called NanoSMS that allows scientists to analyze the molecules secreted by individual cells, providing insights into how these cells communicate and function. By encapsulating single cells and using advanced sensing techniques, the project aims to measure the production of antibodies and other important molecules in real-time. Patients with autoimmune disorders will be particularly relevant, as the research seeks to understand how their immune cells respond to specific antigens. This innovative approach could lead to breakthroughs in understanding immune responses and developing targeted therapies.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with autoimmune disorders or those undergoing treatments that affect their immune system.
Not a fit: Patients with stable, non-autoimmune conditions or those not involved in immune response studies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for autoimmune diseases and better understanding of immune responses in various conditions.
How similar studies have performed: While the approach of analyzing single cell secretomes is innovative, similar methodologies have shown promise in other areas of cellular biology and immunology.
Where this research is happening
RIVERSIDE, UNITED STATES
- UNIVERSITY OF CALIFORNIA RIVERSIDE — RIVERSIDE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FREEDMAN, KEVIN — UNIVERSITY OF CALIFORNIA RIVERSIDE
- Study coordinator: FREEDMAN, KEVIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases