Analyzing lipoproteins and their role in cardiovascular health
Core B: Proteomics and lipoprotein characterization core
This study is looking at different types of fats in your blood to see how they might be linked to heart disease and diabetes, which could help doctors find better ways to diagnose and treat these conditions.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project ID | NIH-10874517 on NIH RePORTER |
What this research studies
This research focuses on the characterization of lipoproteins using advanced mass spectrometry and data analysis techniques. It aims to isolate and measure different types of lipoproteins, including those associated with cardiovascular diseases, to understand their structure and concentration. By employing calibrated ion mobility analysis, the research will quantify various lipoprotein classes and their protein content, which could provide insights into their roles in health and disease. Patients may benefit from the findings as they could lead to improved diagnostics and treatments for conditions like atherosclerosis and diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals at risk for cardiovascular diseases or those with diabetes who may benefit from advanced lipoprotein profiling.
Not a fit: Patients with conditions unrelated to lipoprotein metabolism or cardiovascular health may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for cardiovascular diseases and diabetes.
How similar studies have performed: Previous research has shown success in using similar mass spectrometry techniques for lipoprotein analysis, indicating a promising approach.
Where this research is happening
Seattle, United States
- University of Washington — Seattle, United States (Active)
Researchers
- Principal investigator: Vaisar, Tomas — University of Washington
- Study coordinator: Vaisar, Tomas
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.