Analyzing immune cells from critically ill patients with lung injuries
Patient Sampling and Genomics Core
This study is looking at immune cells from patients with Acute Respiratory Distress Syndrome (ARDS) to better understand how the disease works and affects people, using a safe way to collect lung samples and comparing them with blood samples.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project ID | NIH-10895339 on NIH RePORTER |
What this research studies
This research focuses on collecting and analyzing immune cells called macrophages from patients suffering from Acute Respiratory Distress Syndrome (ARDS) due to conditions like sepsis and pneumonia. The study employs a safe method for obtaining lung samples without invasive procedures, allowing for a better understanding of the disease's severity and progression. Blood samples will also be collected to compare immune responses between lung and blood cells. The goal is to create a comprehensive database that correlates clinical outcomes with detailed immune cell analyses.
Who could benefit from this research
Good fit: Ideal candidates for this research are critically ill patients diagnosed with ARDS or related acute respiratory conditions.
Not a fit: Patients with chronic respiratory conditions or those not experiencing acute respiratory distress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments and management strategies for patients with ARDS.
How similar studies have performed: Previous research has shown promise in using similar approaches to analyze immune responses in critically ill patients, indicating potential for success.
Where this research is happening
Chicago, UNITED STATES
- University of Illinois at Chicago — Chicago, United States (Active)
Researchers
- Principal investigator: Dudek, Steven M — University of Illinois at Chicago
- Study coordinator: Dudek, Steven M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.