Analyzing how proteins interact and form networks in the body
Genome-wide structure-based analysis of protein-protein interactions and networks
['FUNDING_OTHER'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-10991315
This study is looking at how proteins work together in our bodies, which is important for understanding diseases like bacterial infections, and it aims to use computer tools to predict these interactions so we can learn more about how to improve health.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | COLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10991315 on ClinicalTrials.gov |
What this research studies
This research investigates the interactions between proteins and how they form networks that are crucial for various biological processes. By utilizing computational tools and algorithms, the team aims to predict protein-protein interactions on a large scale, which can help in understanding diseases caused by bacterial infections and other conditions. The research combines theoretical approaches with experimental validation to uncover the structural basis of these interactions, potentially leading to new insights in systems biology. Patients may benefit from advancements in understanding how proteins function and interact in the context of their health.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals affected by bacterial infections or related diseases that involve protein interactions.
Not a fit: Patients with conditions unrelated to protein interactions or those not affected by bacterial infections may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for diseases related to protein interactions, including bacterial infections.
How similar studies have performed: Previous research in computational structural biology has shown promise in elucidating protein interactions, indicating that this approach has potential for success.
Where this research is happening
NEW YORK, UNITED STATES
- COLUMBIA UNIVERSITY HEALTH SCIENCES — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: HONIG, BARRY H — COLUMBIA UNIVERSITY HEALTH SCIENCES
- Study coordinator: HONIG, BARRY H
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bacteria infection, bacterial disease, Bacterial Infections