Analyzing brain structure changes in PTSD using advanced imaging techniques
A large sample machine learning network analysis of vertex cortical thickness measures for high resolution definition of PTSD related cortical structure abnormalities
['FUNDING_R21'] · UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS · NIH-10551850
This study is looking at how PTSD changes the brain's structure by examining brain scans from nearly 19,000 people, and it hopes to find specific areas that are affected, which could help improve how we diagnose and treat PTSD.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS (nih funded) |
| Locations | 1 site (TOLEDO, UNITED STATES) |
| Trial ID | NIH-10551850 on ClinicalTrials.gov |
What this research studies
This research investigates how posttraumatic stress disorder (PTSD) affects the structure of the brain by examining cortical thickness in detail. Using advanced machine learning techniques, the study aims to analyze a large database of brain imaging data from nearly 19,000 subjects to identify specific areas of cortical thinning associated with PTSD. By focusing on individual vertex areas of the brain, the research seeks to uncover more precise relationships between brain structure and PTSD symptoms, which could lead to better diagnostic and treatment strategies. Patients may be asked to participate by providing brain imaging data and relevant health information.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with PTSD or those experiencing symptoms related to the disorder.
Not a fit: Patients without PTSD or those who do not have any mental health disorders may not receive benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment options for individuals suffering from PTSD.
How similar studies have performed: Previous research has shown promising results using similar vertex-based imaging techniques to study brain structure in various mental health conditions.
Where this research is happening
TOLEDO, UNITED STATES
- UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS — TOLEDO, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: WANG, XIN — UNIVERSITY OF TOLEDO HEALTH SCI CAMPUS
- Study coordinator: WANG, XIN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Mental disorders, Mental health disorders, Psychiatric Disease, Psychiatric Disorder, psychological disorder