Anal cancer prevention program for people living with HIV

Implementing an Evidence-Based, Multilevel Intervention for Primary Prevention of Anal Cancer among HIV Positive Adults

NIH-funded research Emory University · NIH-11086839

This program helps people living with HIV in Georgia get education, screening follow-up, and clinic support to lower their chance of developing anal cancer.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionEmory University NIH-funded
Lab location1 site (Atlanta, United States)
Project IDNIH-11086839 on NIH RePORTER

What this research studies

You would receive a tailored prevention program delivered through your HIV clinic that combines education, reminders, and changes to clinic workflow to improve timely follow-up after abnormal anal Pap tests. The team will adapt the evidence-based 4 Pillars™ Transformation Program for use in both rural and urban HIV clinics across Georgia. About 365 adults living with HIV aged 18–45 who get care at the participating clinics will be enrolled and followed to see whether care and follow-up improve. The project uses the RE-AIM framework to guide how the program is implemented and measured across clinics.

Who could benefit from this research

Good fit: Adults living with HIV ages 18–45 who receive care at one of the participating HIV clinics in Georgia are the intended participants.

Not a fit: People without HIV, those outside the 18–45 age range, or those who do not get care at the participating clinics are unlikely to be eligible or directly benefit.

Why it matters

Potential benefit: If successful, this program could reduce delays in follow-up care and help lower anal cancer risk among people living with HIV.

How similar studies have performed: The 4 Pillars™ program has improved prevention efforts in other settings, but applying it specifically to anal cancer prevention among people living with HIV is a newer application.

Where this research is happening

Atlanta, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAnal CancerAnus CancerCancers
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.