NIH-funded research R21 grant

An online program to help advanced gynecologic cancer patients manage their fear of disease progression.

Official title: A Blended e-Health Intervention for Fear of Progression in Advanced GYN Cancer

Funded at Beckman Research Institute/city of Hope · NIH-10948016 · Data updated 2026-11-12

This study is testing a supportive online program for women with advanced gynecologic cancer to help them manage their fears about their illness, using group video chats and self-study materials, all led by a nurse to make it easier for patients to access.

More Fear research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionBeckman Research Institute/city of Hope
NIH-funded
Lab location1 site (Duarte, United States)
Project startSeptember 1, 2024
Project endAugust 31, 2026
Funding year2024
Award (this year)$489,500
NIH project number1R21CA293326-01
Project IDNIH-10948016 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with stage III or IV gynecologic cancer who experience significant fear of disease progression.

Less likely to help

Patients with early-stage cancer or those not experiencing fear of disease progression may not benefit from this intervention.

What this research studies

This research investigates a blended e-Health intervention designed to help patients with advanced gynecologic cancer cope with their fear of disease progression (FOP). The program combines group videoconferencing sessions and web-based self-study materials, focusing on Acceptance and Commitment therapy to address emotional well-being and existential concerns. By utilizing a nurse-led approach, the intervention aims to improve accessibility and sustainability for patients who often face significant psychological distress. The study will assess the feasibility and effectiveness of this innovative approach in a randomized pilot format.

Why it matters

Potential benefit: If successful, this research could provide advanced cancer patients with effective tools to manage anxiety and improve their quality of life.

How similar studies have gone: Previous interventions targeting fear of progression in early-stage cancer patients have shown success, but this approach for advanced cancer is novel.

Where this research is happening

  • Beckman Research Institute/city of Hope
    Duarte, United States
    Active

Researchers

  • Principal investigator: Reb, Anne — Beckman Research Institute/city of Hope
  • Study coordinator: Reb, Anne

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.