Advancing Ethical Goals in Society: Implementation Core (care planning for Alzheimer's and related dementias)
Official title: Advancing Ethical Goals In Society (AEGIS) - Implementation Core
Funded at Tufts Medical Center · NIH-11265031 · Data updated 2026-11-12
A nationwide program tests long-term, multi-part strategies to help people with Alzheimer's and related dementias and their families make clearer, more goal-aligned medical decisions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Tufts Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | July 1, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $507,038 |
| NIH project number | 1U19AG090271-01A1 |
| Project ID | NIH-11265031 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults diagnosed with Alzheimer's disease or related dementias who are receiving care in participating health systems.
✕Less likely to help
Patients not involved in ACP processes or in settings not participating in the implementation strategy may see no direct benefit.
What this research studies
This grant supports a pragmatic, longitudinal study in which patients with Alzheimer's disease and related dementias receive a sequence of interventions designed to improve advance care planning and alignment of care with their goals. It builds on prior trials by including larger, more diverse patient groups and clinic-level implementation within real health systems. Researchers will monitor how interventions affect ACP documentation, patient and family satisfaction, and the consistency of care with stated goals over time. The study emphasizes collaboration with clinicians and health systems to understand how workflows and policies influence adoption. Overall, the project aims to make advance care planning more reliable, scalable, and meaningful for ADRD patients and their families.
Why it matters
Potential benefit: If successful, patients with ADRD and their families could experience clearer medical choices and more care aligned with their goals.
How similar studies have gone: Previous trials showed improvements in ACP documentation and patient satisfaction, but results varied and larger, more diverse studies are needed.
Where this research is happening
-
Tufts Medical Center
Boston, United States Active
Researchers
- Principal investigator: Matlock, Daniel D — Tufts Medical Center
- Study coordinator: Matlock, Daniel D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.