Advanced ultrasound technology for better evaluation of rheumatoid arthritis

Ultrasensitive Doppler Ultrasound for Evaluation of Rheumatoid Arthritis

['FUNDING_R21'] · MAYO CLINIC ROCHESTER · NIH-10659056

This study is testing a new ultrasound technology called HUMI that aims to better detect inflammation in the joints of people with rheumatoid arthritis, helping doctors provide more accurate treatment based on what they find.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorMAYO CLINIC ROCHESTER (nih funded)
Locations1 site (ROCHESTER, UNITED STATES)
Trial IDNIH-10659056 on ClinicalTrials.gov

What this research studies

This research focuses on developing a new ultrasound technology called High-sensitivity Ultrasound Microvessel Imaging (HUMI) to improve the evaluation of synovial inflammation in patients with rheumatoid arthritis (RA). Current methods like MRI and traditional Doppler ultrasound have limitations in sensitivity and cost, which can lead to underdiagnosis. The HUMI technology aims to provide a more accurate and comprehensive assessment by detecting microvessels in 3D with high sensitivity, using advanced imaging techniques and algorithms. This could lead to better management of RA by guiding therapy more effectively based on precise evaluations.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with rheumatoid arthritis who require regular assessments of joint inflammation.

Not a fit: Patients with rheumatoid arthritis who are not undergoing regular evaluations or those with other unrelated conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and improved treatment strategies for patients with rheumatoid arthritis.

How similar studies have performed: Other research has shown promising results with advanced ultrasound technologies in similar applications, indicating potential for success in this novel approach.

Where this research is happening

ROCHESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Autoimmune Diseases, autoimmune disorder, autoimmunity disease

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.