Advanced Light Sources for Detailed Medical Imaging

Flexible dual-duration multi-wavelength fiber sources for nonlinear and multimodal imaging

['FUNDING_R01'] · UNIVERSITY OF ROCHESTER · NIH-11194323

This work develops new light sources to create clearer, more detailed images of living tissues, helping doctors better understand conditions like heart disease and cancer.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF ROCHESTER (nih funded)
Locations1 site (ROCHESTER, UNITED STATES)
Trial IDNIH-11194323 on ClinicalTrials.gov

What this research studies

Our goal is to create powerful and adaptable fiber-optic light sources that can produce highly detailed images of living tissues. These new light sources will use special imaging techniques to see deep inside the body without needing to remove tissue or use dyes. By combining different imaging methods, we can gather a rich variety of information about molecules, structures, and how cells function. This advanced imaging could help identify diseases like atherosclerosis and cancer more accurately and reveal important signs that are currently hard to see.

Who could benefit from this research

Good fit: This foundational technology development does not directly involve patient participation, but future applications would benefit patients needing advanced diagnostic imaging for conditions like atherosclerosis, neurological diseases, or cancer.

Not a fit: Patients not affected by conditions requiring advanced tissue imaging, such as atherosclerosis or cancer, would not directly benefit from this specific technology development.

Why it matters

Potential benefit: If successful, this technology could lead to earlier and more precise diagnoses for conditions like heart disease and cancer, potentially improving treatment outcomes.

How similar studies have performed: This research builds upon recent proof-of-concept demonstrations by the principal investigators, aiming to establish a new suite of ultra-short pulse generation technologies.

Where this research is happening

ROCHESTER, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Atherosclerotic Cardiovascular Disease, Cancers

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.