Advanced lab technology team analyzing coronavirus and patient samples
Core B - Technology Core
This team uses cutting-edge lab techniques to study virus and patient samples to find signs of COVID-19 severity and possible targets for treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11247098 on NIH RePORTER |
What this research studies
The Technology Core runs high-end 'omics' tests (like proteomics, transcriptomics, and epigenetics) and viral reverse genetics on samples collected from people and lab models. They process blood, respiratory, and cultured-cell samples and create engineered viruses to study how the virus behaves. Data from these lab tests are combined with patients' clinical information to look for markers linked to worse illness and potential points for drugs. Results and datasets are shared with other project teams to guide modeling and therapy development.
Who could benefit from this research
Good fit: Ideal participants are people with confirmed SARS-CoV-2 infection who can provide blood or respiratory samples and allow access to their clinical information.
Not a fit: People without COVID-19 or those expecting immediate personal treatment benefit are unlikely to gain direct clinical benefit from participating.
Why it matters
Potential benefit: If successful, this work could reveal biomarkers that predict who will get sicker and identify molecular targets for new COVID-19 treatments.
How similar studies have performed: Prior omics and viral genetics studies have identified biomarkers and viral features for COVID-19, but integrating multiple data types across patients is still advancing and may reveal new insights.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Garcia-Sastre, Adolfo — Icahn School of Medicine at Mount Sinai
- Study coordinator: Garcia-Sastre, Adolfo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.