Advanced imaging technology for studying living tissues
Official title: Light Sheet Microscope for Multi-View Imaging of Living and Optically Cleared Samples
Funded at Harvard Medical School · NIH-10853453 · Data updated 2026-11-12
This study is all about using a special type of microscope that helps scientists take detailed 3D pictures of whole organs and thick tissues, which can really help us understand how cells work and develop, especially in areas like the immune system and growth.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Harvard Medical School NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | August 15, 2024 |
| Project end | August 14, 2025 |
| Funding year | 2024 |
| Award (this year) | $646,616 |
| NIH project number | 1S10OD036362-01 |
| Project ID | NIH-10853453 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions related to immune system dysfunction or developmental disorders.
✕Less likely to help
Patients with conditions that do not involve cellular interactions or tissue imaging may not receive direct benefits from this research.
What this research studies
This research focuses on acquiring a state-of-the-art light sheet microscope to enhance imaging capabilities for whole organs and thick tissue samples. By utilizing this technology, researchers can observe cellular components in a three-dimensional context, which is crucial for understanding their development and function. The microscope allows for high-speed imaging with minimal damage to samples, making it suitable for both live and fixed tissues. This innovative approach aims to improve insights into various biomedical fields, including immune cell interactions and developmental biology.
Why it matters
Potential benefit: If successful, this research could significantly advance our understanding of cellular interactions and functions in living tissues, leading to improved treatments for various diseases.
How similar studies have gone: Previous research has shown that advanced imaging techniques like light-sheet microscopy can provide valuable insights in biomedical research, indicating a strong potential for success in this approach.
Where this research is happening
-
Harvard Medical School
Boston, United States Active
Researchers
- Principal investigator: Montero Llopis, Paula de la Milagrosa — Harvard Medical School
- Study coordinator: Montero Llopis, Paula de la Milagrosa
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.