Advanced imaging of brain tissue to understand mental health disorders
Official title: Request for a ThermoFisher Helios 5UC DualBeam
Funded at University of Pittsburgh at Pittsburgh · NIH-10719755 · Data updated 2026-11-12
This study is looking to get a super advanced electron microscope to take really detailed 3D pictures of brain tissue, which will help scientists understand how the brain works and how it relates to mental health issues.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pittsburgh at Pittsburgh NIH-funded |
| Lab location | 1 site (Pittsburgh, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $600,000 |
| NIH project number | 1S10MH133575-01 |
| Project ID | NIH-10719755 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research are individuals with psychiatric disorders or mental health conditions.
✕Less likely to help
Patients with acute medical conditions unrelated to mental health may not receive benefit from this research.
What this research studies
This research aims to acquire a state-of-the-art electron microscope to create detailed 3D images of brain tissue at a nanometer scale. By using this advanced imaging technology, researchers will be able to study the intricate structures of the brain and how they relate to complex behaviors and psychiatric disorders. The focus is on generating high-resolution connectomic maps that can reveal the underlying mechanisms of mental health conditions. This approach will enhance our understanding of brain function and dysfunction in relation to mental illnesses.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating mental health disorders.
How similar studies have gone: While the application of this specific technology in neuroscience is relatively new, similar advanced imaging techniques have shown promise in enhancing our understanding of brain disorders.
Where this research is happening
-
University of Pittsburgh at Pittsburgh
Pittsburgh, United States Active
Researchers
- Principal investigator: Glausier, Jill Renee' — University of Pittsburgh at Pittsburgh
- Study coordinator: Glausier, Jill Renee'
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.