Administrative Core of the Penn HPPC to advance precision pain research
Official title: Administrative Core
Funded at University of Pennsylvania · NIH-11564962 · Data updated 2026-11-12
A focused administrative core supports a center studying human trigeminal pain pathways to help improve migraine understanding and future treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 20, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $219,016 |
| NIH project number | 4U19NS135528-02 |
| Project ID | NIH-11564962 on NIH RePORTER |
Who could benefit from this research
✓Could help
People with migraine or those at risk who could participate in future translational studies or provide human tissue samples related to trigeminal pain.
✕Less likely to help
Patients not involved in center activities or whose conditions are outside trigeminal pain pathways may not directly benefit.
What this research studies
This grant funds the administrative backbone of the Penn Human Precision Pain Center, which brings experts together to study human trigeminal neurons at baseline and during migraine. The core will organize resources, leadership, budgeting, and coordination across multiple projects and international collaborators. By facilitating data sharing and oversight, it aims to streamline discovery of molecular and physiological factors that drive migraine pain in people. This work builds on existing single-soma RNA sequencing efforts to create a coordinated, patient-centered research program.
Why it matters
Potential benefit: If successful, the center could accelerate the development of targeted migraine therapies by clarifying human trigeminal biology and pain signals.
How similar studies have gone: Previous work on human pain genes and cells lays a foundation, and this center builds on that by coordinating multiple projects for broader impact.
Where this research is happening
-
University of Pennsylvania
Philadelphia, United States Active
Researchers
- Principal investigator: Luo, Wenqin — University of Pennsylvania
- Study coordinator: Luo, Wenqin
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.