Administrative Core for APOE and Alzheimer's disease research consortium
Official title: Core A: Administrative Core
Funded at Mayo Clinic Jacksonville · NIH-11418797 · Data updated 2026-11-12
A large, multi-project NIH program is led from Mayo Clinic Jacksonville to keep the entire APOE- and Alzheimer’s-focused research organized, compliant, and Collaborative.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Jacksonville NIH-funded |
| Lab location | 1 site (Jacksonville, United States) |
| Project start | September 1, 2021 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $297,146 |
| NIH project number | 2U19AG069701-06 |
| Project ID | NIH-11418797 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals with or at risk for Alzheimer's disease or age-related cognitive decline who may participate in future APOE-focused studies or trials.
✕Less likely to help
This administrative core does not directly recruit patients or test treatments.
What this research studies
This grant supports the administrative backbone of a U19 program that coordinates multiple cores and projects studying protective APOE variants and other genetic factors in Alzheimer’s disease and age-related cognitive decline. It covers governance, budgeting, regulatory compliance, scientific direction, reporting to NIH, and community engagement. The goal is to smooth collaboration and ensure rigorous, reproducible science across all teams working on APOE-related risk and protection in AD.
Why it matters
Potential benefit: If successful, the program could accelerate discoveries about how APOE variants influence Alzheimer’s risk and aging, informing future therapies and risk assessment.
How similar studies have gone: Prior APOE-focused research has shown that genetic context can influence disease trajectory, supporting the value of coordinated, multi-project efforts.
Where this research is happening
-
Mayo Clinic Jacksonville
Jacksonville, United States Active
Researchers
- Principal investigator: Kanekiyo, Takahisa — Mayo Clinic Jacksonville
- Study coordinator: Kanekiyo, Takahisa
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.