NIH-funded research R01 grant

Adaptive PTSD care paths to reach more patients in routine clinics

Official title: Adaptive interventions to improve posttraumatic stress (PTSD) treatment access, engagement, and effectiveness in routine care

Funded at Boston Medical Center · NIH-11380636 · Data updated 2026-11-12

A patient-friendly plan tests how to sequence simple, scalable PTSD treatments in regular clinics to help more people start and stay in care.

More PTSD research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston Medical Center
NIH-funded
Lab location1 site (Boston, United States)
Project startAugust 1, 2025
Project endJuly 31, 2030
Funding year2026
Award (this year)$863,400
NIH project number5R01MH138549-02
Project IDNIH-11380636 on NIH RePORTER

Who could benefit from this research

Could help

Adults with PTSD who receive care in resource-constrained primary care clinics and are open to digital and brief, scalable treatments.

Less likely to help

Patients in clinics with abundant mental health resources or those who prefer non-brief interventions may see less benefit.

What this research studies

This project tests a flexible, stepped approach that starts with a digital behavioral health tool and adds brief, in-person PTSD treatments as needed, all within typical healthcare settings. It aims to make evidence-based PTSD care more accessible in primary care where resources are limited. The study will adapt treatment steps based on each person’s needs and response, to fit real-world clinics without overburdening staff. If successful, it could mean faster access, better engagement, and improved outcomes for patients with PTSD in everyday care. The research builds on prior work to tailor PTSD care pathways for diverse patients in routine practice.

Why it matters

Potential benefit: If successful, patients could experience faster access to effective PTSD care and better engagement with treatment in their regular clinics.

How similar studies have gone: Similar adaptive approaches have shown promise in other conditions, but applying adaptive PTSD care pathways in routine clinics is still being explored.

Where this research is happening

  • Boston Medical Center
    Boston, United States
    Active

Researchers

  • Principal investigator: Valentine, Sarah E — Boston Medical Center
  • Study coordinator: Valentine, Sarah E

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.