Acquiring advanced technology for studying complex proteins
Acquisition of a dedicated and integrated HD-MS instrument
['FUNDING_OTHER'] · CASE WESTERN RESERVE UNIVERSITY · NIH-11100513
This study is working to get a new, advanced machine that will help scientists better understand how proteins behave in diseases like Alzheimer's and other complex conditions, making their research more accurate and efficient.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CASE WESTERN RESERVE UNIVERSITY (nih funded) |
| Locations | 1 site (CLEVELAND, UNITED STATES) |
| Trial ID | NIH-11100513 on ClinicalTrials.gov |
What this research studies
This research aims to obtain a cutting-edge mass spectrometry system that will enhance the study of complex protein structures, particularly those related to various diseases. The new equipment will replace outdated technology, allowing researchers to conduct more efficient and reliable experiments on protein interactions and abnormalities. By focusing on hydrogen/deuterium exchange studies, this project will support a wide range of biomedical research efforts at Case Western Reserve University and affiliated institutions. This technology is crucial for understanding protein behavior in conditions like neurodegenerative disorders and other complex diseases.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals under 15 years of age with conditions related to abnormal protein folding or neurodegenerative diseases.
Not a fit: Patients with conditions unrelated to protein misfolding or those over the age of 15 may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating diseases associated with protein misfolding and aggregation.
How similar studies have performed: Other research utilizing advanced mass spectrometry techniques has shown promise in understanding complex biological systems, indicating that this approach is likely to yield valuable insights.
Where this research is happening
CLEVELAND, UNITED STATES
- CASE WESTERN RESERVE UNIVERSITY — CLEVELAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MIYAGI, MASARU — CASE WESTERN RESERVE UNIVERSITY
- Study coordinator: MIYAGI, MASARU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: bacteria infection, bacterial disease, Bacterial Infections