Access for All in ALS: Coordinating Center powering a national ALS research network
Official title: Access for All in ALS (ALL ALS) East Clinical Coordinating Center
Funded at Massachusetts General Hospital · NIH-11621106 · Data updated 2026-11-12
A national ALS research program will coordinate clinical data and a long-term study of ALS patients and at-risk gene carriers to improve understanding and future treatments.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 25, 2023 |
| Project end | September 24, 2028 |
| Funding year | 2026 |
| Award (this year) | $22,407,270 |
| NIH project number | 3OT2NS136938-01S3 |
| Project ID | NIH-11621106 on NIH RePORTER |
Who could benefit from this research
✓Could help
People diagnosed with ALS and healthy individuals who carry known ALS gene mutations and are at high risk.
✕Less likely to help
Individuals without ALS or without known high-risk mutations may not directly benefit.
What this research studies
This grant creates a Clinical and Data Coordinating Center and a 30-site ALS Clinical Research Consortium to support a large, long-term study. It will enroll 2000+ people with ALS and 500 asymptomatic gene-carrier individuals, collecting clinical data and biomarkers over time. The effort builds on existing ALS networks to share data, biospecimens, and best practices to accelerate discoveries that could benefit people living with ALS and those at high risk.
Why it matters
Potential benefit: Could lead to earlier detection, better biomarkers, and more effective therapies for ALS.
How similar studies have gone: Existing ALS observational studies and biobanking have demonstrated value in understanding disease progression and biomarkers, supporting this broader coordinated effort.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Berry, James Dale — Massachusetts General Hospital
- Study coordinator: Berry, James Dale
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.