A vaccine to prevent oxycodone overdose using bacteriophage technology
Bacteriophage virus-like particle based vaccines against oxycodone
This study is testing a new vaccine that could help prevent overdoses from oxycodone, a drug that some people misuse, and it's designed for anyone struggling with opioid use disorder who wants to stay safe and healthy.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10995261 on NIH RePORTER |
What this research studies
This research investigates a novel vaccine designed to prevent overdoses from oxycodone, a commonly abused opioid. It utilizes bacteriophage virus-like particles to create a highly immunogenic vaccine that aims to block the effects of oxycodone in the body. The study will assess how well this vaccine can prevent the drug from crossing the blood-brain barrier, which is crucial for its effectiveness. Patients who receive this vaccine may have a reduced risk of overdose and improved outcomes in managing opioid use disorder.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with a history of opioid use disorder or those at high risk of oxycodone overdose.
Not a fit: Patients who are not using opioids or who have no history of opioid use disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a groundbreaking vaccine that significantly reduces the risk of oxycodone overdose for patients struggling with opioid use disorder.
How similar studies have performed: While vaccines targeting opioids are a novel approach, preliminary studies have shown promise in similar vaccine strategies, indicating potential for success.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Romano, Isabella — University of New Mexico Health Scis Ctr
- Study coordinator: Romano, Isabella
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.