A Saliva Test for Early Sjögren's Disease and Related Conditions
Saliva Anti-SSA/Ro and Anti-SSB/La for Early Detection of Sjögren’s and SICCA Syndromes
This project is developing a new saliva test to help find Sjögren's Disease and a related condition called autoimmune-Sicca Syndrome much earlier.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11193537 on NIH RePORTER |
What this research studies
Many people with Sjögren's Disease and a related condition called autoimmune-Sicca Syndrome experience long delays in getting a diagnosis because current tests are often invasive or not sensitive enough early on. This project is working on a new, simpler saliva test that looks for specific markers, called autoantibodies, that are linked to these conditions. By using a special technology, this saliva test could help doctors identify these diseases much sooner than current methods. This could lead to earlier treatment and better management of symptoms for patients.
Who could benefit from this research
Good fit: Patients who have been diagnosed with or suspect they have Sjögren's Disease or autoimmune-Sicca Syndrome might be ideal candidates for future participation.
Not a fit: Patients without symptoms or a risk of Sjögren's Disease or autoimmune-Sicca Syndrome would likely not receive direct benefit from this specific diagnostic tool.
Why it matters
Potential benefit: If successful, this saliva test could provide a non-invasive and earlier way to diagnose Sjögren's Disease and autoimmune-Sicca Syndrome, potentially leading to faster treatment and improved patient outcomes.
How similar studies have performed: Preliminary data from this research team has shown promising results for the saliva-based test in detecting markers for Sjögren's Disease.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Wong, David T — University of California Los Angeles
- Study coordinator: Wong, David T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.