A new ventilation system to improve breathing in patients with Acute Respiratory Distress Syndrome.

VENTSAFE™ Life Saving Ventilation for the Treatment of ARDS

NIH-funded research Liberandum Technologies, INC. · NIH-11175442

This study is testing a new ventilation system called VENTSAFE™ that aims to help people with Acute Respiratory Distress Syndrome breathe better and feel safer, while reducing the need for heavy sedation and minimizing lung injury.

Quick facts

Grant typeSbir 1 grant
Study typeNIH-funded research
Funding institutionLiberandum Technologies, INC. NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11175442 on NIH RePORTER

What this research studies

This research aims to develop a novel ventilation system called VENTSAFE™ that provides controlled airflow to improve oxygenation in patients suffering from Acute Respiratory Distress Syndrome (ARDS). The system is designed to minimize lung injury caused by traditional ventilation methods by using a bidirectional synchronous flow-controlled approach, which allows for gentle gas exchange without the harmful effects of conventional ventilation. Patients will benefit from a potentially safer and more effective method of ventilation that reduces the need for sedation and paralysis. The research involves testing the device's performance in a controlled environment to ensure its efficacy and safety.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults aged 21 and older who are experiencing Acute Respiratory Distress Syndrome.

Not a fit: Patients with respiratory conditions other than ARDS or those who are not adults may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a safer ventilation method that significantly improves survival rates for patients with ARDS.

How similar studies have performed: While the approach is innovative, similar technologies have shown promise in improving ventilation outcomes, indicating potential for success.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acute Respiratory Distress SyndromeAdult Respiratory Distress Syndrome
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.