A new ventilation system to improve breathing in patients with Acute Respiratory Distress Syndrome.
Official title: VENTSAFE™ Life Saving Ventilation for the Treatment of ARDS
Funded at Liberandum Technologies, INC. · NIH-11175442 · Data updated 2026-11-12
This study is testing a new ventilation system called VENTSAFE™ that aims to help people with Acute Respiratory Distress Syndrome breathe better and feel safer, while reducing the need for heavy sedation and minimizing lung injury.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Liberandum Technologies, INC. NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $288,855 |
| NIH project number | 5R43HL176331-02 |
| Project ID | NIH-11175442 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are experiencing Acute Respiratory Distress Syndrome.
✕Less likely to help
Patients with respiratory conditions other than ARDS or those who are not adults may not benefit from this research.
What this research studies
This research aims to develop a novel ventilation system called VENTSAFE™ that provides controlled airflow to improve oxygenation in patients suffering from Acute Respiratory Distress Syndrome (ARDS). The system is designed to minimize lung injury caused by traditional ventilation methods by using a bidirectional synchronous flow-controlled approach, which allows for gentle gas exchange without the harmful effects of conventional ventilation. Patients will benefit from a potentially safer and more effective method of ventilation that reduces the need for sedation and paralysis. The research involves testing the device's performance in a controlled environment to ensure its efficacy and safety.
Why it matters
Potential benefit: If successful, this research could lead to a safer ventilation method that significantly improves survival rates for patients with ARDS.
How similar studies have gone: While the approach is innovative, similar technologies have shown promise in improving ventilation outcomes, indicating potential for success.
Where this research is happening
-
Liberandum Technologies, INC.
San Francisco, United States Active
Researchers
- Principal investigator: Barker, Dean Antony — Liberandum Technologies, INC.
- Study coordinator: Barker, Dean Antony
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.