A new tool to treat kidney diseases using electrical stimulation
A novel electroceutical tool for treatment of kidney-based diseases
This study is working on a new device that helps treat kidney problems by gently adjusting nerve activity, which could improve kidney function and lower blood pressure for people dealing with hypertension and related kidney issues.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Minnesota NIH-funded |
| Lab location | 1 site (Minneapolis, United States) |
| Project ID | NIH-10455432 on NIH RePORTER |
What this research studies
This research focuses on developing an innovative electroceutical device aimed at treating kidney diseases by modulating nerve activity. The approach involves creating a closed-loop feedback system that can adjust the stimulation of renal nerves, potentially improving kidney function and lowering blood pressure. By utilizing insights from preclinical models and computational tools, the research aims to translate these findings into a practical, implantable technology for patients suffering from hypertension and related kidney disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include patients with hypertension and kidney-related conditions who may benefit from neuromodulation therapies.
Not a fit: Patients with non-neurologically mediated kidney diseases or those who do not respond to electrical stimulation therapies may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a non-invasive treatment option for patients with kidney diseases and hypertension, improving their overall health and quality of life.
How similar studies have performed: Previous clinical trials have shown success with renal denervation techniques, indicating that neuromodulation approaches may also be effective in treating kidney-related diseases.
Where this research is happening
Minneapolis, United States
- University of Minnesota — Minneapolis, United States (Active)
Researchers
- Principal investigator: Osborn, John W — University of Minnesota
- Study coordinator: Osborn, John W
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.