A new probiotic treatment for Sjögren's Syndrome

A Novel Probiotic for the Treatment of Sjogren's Syndrome

NIH-funded research Rise Therapeutics, LLC · NIH-10615156

This study is testing a new probiotic treatment to help people with Sjögren's Syndrome feel better by boosting their immune system, and it could be taken as a drink to improve daily life.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionRise Therapeutics, LLC NIH-funded
Lab location1 site (Rockville, UNITED STATES)
Project IDNIH-10615156 on NIH RePORTER

What this research studies

This research aims to develop a novel probiotic therapy using L. lactis to treat Sjögren's Syndrome, a chronic autoimmune disease that affects the salivary and lacrimal glands. The approach focuses on enhancing the immune response to alleviate symptoms and prevent further complications associated with the disease. By stimulating regulatory cells, the treatment seeks to provide a more effective solution than current therapies, which mainly involve symptom management. Patients may receive this probiotic orally, potentially improving their quality of life.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with Sjögren's Syndrome, particularly those experiencing significant symptoms.

Not a fit: Patients with other autoimmune conditions unrelated to Sjögren's Syndrome may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from Sjögren's Syndrome.

How similar studies have performed: While the use of probiotics in autoimmune diseases is an emerging field, this specific approach using L. lactis for Sjögren's Syndrome is novel and has not been extensively tested.

Where this research is happening

Rockville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autoimmune Diseasesautoimmune disorderautoimmunity disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.