A new probiotic treatment for Sjögren's Syndrome
Official title: A Novel Probiotic for the Treatment of Sjogren's Syndrome
Funded at Rise Therapeutics, LLC · NIH-10615156 · Data updated 2026-11-12
This study is testing a new probiotic treatment to help people with Sjögren's Syndrome feel better by boosting their immune system, and it could be taken as a drink to improve daily life.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rise Therapeutics, LLC NIH-funded |
| Lab location | 1 site (Rockville, UNITED STATES) |
| Project start | May 12, 2021 |
| Project end | April 30, 2026 |
| Funding year | 2023 |
| Award (this year) | $947,701 |
| NIH project number | 5SB1DE030833-03 |
| Project ID | NIH-10615156 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with Sjögren's Syndrome, particularly those experiencing significant symptoms.
✕Less likely to help
Patients with other autoimmune conditions unrelated to Sjögren's Syndrome may not benefit from this research.
What this research studies
This research aims to develop a novel probiotic therapy using L. lactis to treat Sjögren's Syndrome, a chronic autoimmune disease that affects the salivary and lacrimal glands. The approach focuses on enhancing the immune response to alleviate symptoms and prevent further complications associated with the disease. By stimulating regulatory cells, the treatment seeks to provide a more effective solution than current therapies, which mainly involve symptom management. Patients may receive this probiotic orally, potentially improving their quality of life.
Why it matters
Potential benefit: If successful, this research could provide a new, effective treatment option for patients suffering from Sjögren's Syndrome.
How similar studies have gone: While the use of probiotics in autoimmune diseases is an emerging field, this specific approach using L. lactis for Sjögren's Syndrome is novel and has not been extensively tested.
Where this research is happening
-
Rise Therapeutics, LLC
Rockville, United States Active
Researchers
- Principal investigator: Fanger, Gary — Rise Therapeutics, LLC
- Study coordinator: Fanger, Gary
Related research
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Improving saliva and tear production in Sjögren's syndrome
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.