A new probiotic treatment for rheumatoid arthritis
A Novel Immunological-Directed Biotherapy for Treating Rheumatoid Arthritis
['FUNDING_SBIR_2'] · RISE THERAPEUTICS, LLC · NIH-11076391
This study is testing a new probiotic treatment using L. lactis to help people with rheumatoid arthritis by calming down the immune system to reduce inflammation and joint damage, with the hope of providing lasting relief from symptoms.
Quick facts
| Phase | ['FUNDING_SBIR_2'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | RISE THERAPEUTICS, LLC (nih funded) |
| Locations | 1 site (Rockville, UNITED STATES) |
| Trial ID | NIH-11076391 on ClinicalTrials.gov |
What this research studies
This research aims to develop a novel probiotic-based therapy using L. lactis to treat rheumatoid arthritis (RA), a chronic inflammatory condition affecting the joints. The approach focuses on regulating specific immune cells to reduce inflammation and prevent damage to the body's own tissues. By targeting the immune response, the therapy seeks to provide long-term relief from symptoms and potentially reduce the need for ongoing biologic treatments. Patients will be monitored for their response to this innovative oral immunotherapy.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with rheumatoid arthritis who have not responded adequately to existing treatments.
Not a fit: Patients with rheumatoid arthritis who are currently in remission or those who do not have a confirmed diagnosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to a more effective and safer treatment option for patients with rheumatoid arthritis.
How similar studies have performed: While the use of probiotics in autoimmune diseases is an emerging field, this specific approach using L. lactis for rheumatoid arthritis is novel and has not been extensively tested in prior studies.
Where this research is happening
Rockville, UNITED STATES
- RISE THERAPEUTICS, LLC — Rockville, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FANGER, GARY — RISE THERAPEUTICS, LLC
- Study coordinator: FANGER, GARY
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Autoimmune Diseases