A new microscope for imaging brain activity

Microscope system for large scale optical imaging of neuronal activity using kilohertz frame rates

['FUNDING_SBIR_2'] · MICROBRIGHTFIELD, LLC · NIH-11003971

This study is testing a new type of microscope that helps scientists see how brain cells talk to each other in real-time, which could help us understand brain function better and find new ways to treat brain disorders.

Quick facts

Phase['FUNDING_SBIR_2']
Study typeNih_funding
SexAll
SponsorMICROBRIGHTFIELD, LLC (nih funded)
Locations1 site (WILLISTON, UNITED STATES)
Trial IDNIH-11003971 on ClinicalTrials.gov

What this research studies

This research focuses on developing the 2P-ActivityScope™, an advanced microscope that utilizes a novel technology called SLAP2 to capture high-resolution images of neuronal activity in real-time. By employing fluorescent indicators, this microscope can visualize how neurons communicate and process information at an unprecedented speed and detail. This technology aims to enhance our understanding of brain function and could lead to breakthroughs in treating brain disorders. The research involves both in vivo and in vitro imaging techniques to study neuronal behavior.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with neurological disorders or conditions affecting brain function, as they may benefit from the insights gained through this advanced imaging technology.

Not a fit: Patients with non-neurological conditions or those not affected by brain disorders may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could significantly advance our understanding of brain function and lead to improved treatments for various neurological conditions.

How similar studies have performed: Other research has shown success with advanced imaging technologies in neuroscience, but the specific approach of the 2P-ActivityScope is novel and untested in a commercial context.

Where this research is happening

WILLISTON, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Brain Diseases, Brain Disorders

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.