A New Imaging Method for Understanding Cancer and Autoimmune Diseases
Development of a New Multiplexed Imaging Strategy for Immunoprofiling using Raman-Active Nanoparticles
This project creates a new way to look closely at patient tissue to better understand diseases like cancer and autoimmune conditions.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Southern California NIH-funded |
| Lab location | 1 site (Los Angeles, UNITED STATES) |
| Project ID | NIH-11112526 on NIH RePORTER |
What this research studies
This project aims to develop a new imaging technology that can provide very detailed molecular information from a patient's tissue sample. This technology uses special nanoparticles and light to reveal many molecular markers and their exact location within the tissue. Doctors could use this information from a single image to better understand a patient's disease and choose the most effective treatments. It could also help identify new patterns in tissue that predict how a disease will progress or how well a patient might respond to therapy, offering a unique diagnostic approach.
Who could benefit from this research
Good fit: Patients with cancer or autoimmune diseases whose tissue samples could be analyzed using this advanced imaging technique would be ideal candidates.
Not a fit: Patients who do not have tissue samples available for analysis or whose conditions are not related to the specific molecular markers being studied may not directly benefit from this particular imaging method.
Why it matters
Potential benefit: If successful, this technology could help doctors make more informed decisions about treatment plans for patients with cancer and autoimmune diseases, potentially leading to more effective therapies.
How similar studies have performed: While components of this technology are established, this specific multiplexed imaging strategy for high-content spatial profiling in histology is presented as a novel and innovative approach.
Where this research is happening
Los Angeles, UNITED STATES
- University of Southern California — Los Angeles, United States (Active)
Researchers
- Principal investigator: Zavaleta, Cristina L. — University of Southern California
- Study coordinator: Zavaleta, Cristina L.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.