A new bandage to prevent infections in burn wounds
Official title: A Compliant Superhydrophobic Antimicrobial Photodynamic Therapy Bandage for the Prevention of Multidrug Resistant Wound Infections
Funded at Singleto2 Therapeutics, LLC · NIH-10920772 · Data updated 2026-11-12
This study is testing a new type of bandage that helps prevent infections in burn wounds by using light to kill harmful bacteria, making it safer and more effective for healing without relying on traditional antibiotics.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Singleto2 Therapeutics, LLC NIH-funded |
| Lab location | 1 site (Summit, UNITED STATES) |
| Project start | April 12, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $300,000 |
| NIH project number | 1R41AI183969-01 |
| Project ID | NIH-10920772 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with burn wounds who are at risk of developing multidrug-resistant infections.
✕Less likely to help
Patients with non-burn related wounds or those not at risk for multidrug-resistant infections may not benefit from this research.
What this research studies
This research focuses on developing an innovative bandage designed to prevent infections caused by multidrug-resistant bacteria in burn wounds. The bandage utilizes antimicrobial photodynamic therapy (aPDT) by delivering airborne singlet oxygen, which effectively kills bacteria without introducing drugs into the wound. This approach minimizes the risk of bacterial resistance and enhances the healing process. The bandage's unique superhydrophobic design allows for controlled delivery of treatment while reducing direct contact with the wound.
Why it matters
Potential benefit: If successful, this research could significantly reduce the incidence of infections in burn patients, leading to better recovery outcomes.
How similar studies have gone: Previous research has shown promise with antimicrobial photodynamic therapy, but this specific approach using a superhydrophobic bandage is novel.
Where this research is happening
-
Singleto2 Therapeutics, LLC
Summit, United States Active
Researchers
- Principal investigator: Xu, Qianfeng — Singleto2 Therapeutics, LLC
- Study coordinator: Xu, Qianfeng
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.