A new approach to prevent opioid misuse in cancer patients

A Novel Intervention for Avoidance-Related Opioid Misuse in Patients with Cancer

NIH-funded research Dana-Farber Cancer Inst · NIH-10898087

This study is looking for ways to help cancer patients manage their pain safely without misusing opioids, using a friendly approach called Acceptance and Commitment Therapy to support their mental well-being.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionDana-Farber Cancer Inst NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10898087 on NIH RePORTER

What this research studies

This research focuses on addressing the issue of opioid misuse among cancer patients, which can lead to serious health complications and the risk of developing substance use disorder. The study aims to develop and test a behavioral intervention based on Acceptance and Commitment Therapy (ACT) that specifically targets the psychological factors contributing to opioid misuse in this population. By refining and piloting this intervention, the researchers hope to provide a tailored solution that helps cancer patients manage their pain effectively while minimizing the risk of misuse. The ultimate goal is to improve patient outcomes and quality of life for those undergoing opioid therapy.

Who could benefit from this research

Good fit: Ideal candidates for this research are cancer patients who are currently prescribed opioids and may be experiencing anxiety or depression.

Not a fit: Patients who are not currently using opioids or those without a cancer diagnosis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce the risk of opioid misuse and improve the overall health and well-being of cancer patients.

How similar studies have performed: While there is ongoing research in opioid misuse, this specific approach targeting cancer patients with psychological suffering is novel and has not been extensively tested.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Advanced Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.