NIH-funded research Sbir 2 grant

A device for taking repeated biopsies of glioblastoma tumors

Official title: Tumor Monorail Device for Serial Glioblastoma Biopsy

Funded at Exvade Bioscience, INC. · NIH-11174633 · Data updated 2026-11-12

This study is testing a new device called the Tumor Monorail that helps doctors take safe and precise samples from glioblastoma tumors, making it easier to track how the tumor is changing and how well treatments are working, ultimately aiming to improve care for patients like you.

More Glioblastoma research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionExvade Bioscience, INC.
NIH-funded
Lab location1 site (Atlanta, United States)
Project startAugust 1, 2023
Project endAugust 31, 2026
Funding year2024
Award (this year)$999,360
NIH project number4R44CA285039-02
Project IDNIH-11174633 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are patients diagnosed with glioblastoma who require ongoing monitoring of their tumor status.

Less likely to help

Patients with non-glioblastoma brain tumors or those who are not undergoing treatment for glioblastoma may not benefit from this research.

What this research studies

This research focuses on developing the Tumor Monorail, a device designed to enable safe and accurate serial biopsies of glioblastoma tumors. By providing real-time access to tumor material, the device aims to improve the monitoring of tumor progression and treatment response, which is crucial for adjusting therapies to enhance patient outcomes. The approach involves leveraging established materials and designs that have been proven safe in clinical settings, ensuring reliability and biocompatibility. This innovative method seeks to address the limitations of current biopsy techniques and imaging methods that often fail to provide comprehensive insights into tumor behavior.

Why it matters

Potential benefit: If successful, this research could significantly improve the management of glioblastoma by allowing for timely adjustments to treatment based on accurate tumor monitoring.

How similar studies have gone: While the concept of serial biopsies is not entirely novel, the specific application of the Tumor Monorail device represents a new approach that has not been extensively tested in clinical settings.

Where this research is happening

  • Exvade Bioscience, INC.
    Atlanta, United States
    Active

Researchers

  • Principal investigator: Meehan, Sean — Exvade Bioscience, INC.
  • Study coordinator: Meehan, Sean

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.