A consortium to advance gene therapy for rare neurological disorders

Gene Therapy Consortium (GTC) for Gene-Based Clinical Trials Conducted within NeuroNEXT

NIH-funded research Massachusetts General Hospital · NIH-11288659

This study is creating a team of experts to help develop new gene therapies for very rare neurological disorders in both kids and adults, making it easier for researchers to bring new treatment options to patients who really need them.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11288659 on NIH RePORTER

What this research studies

This research aims to establish a Gene Therapy Consortium that will provide expert guidance on clinical trials for gene therapies targeting ultra-rare neurological disorders in both adults and children. The consortium will collaborate with various stakeholders, including government and academic institutions, to streamline the development and implementation of these therapies. By focusing on innovative trial designs and supporting researchers throughout the trial process, the consortium seeks to bring new treatment options to patients with conditions that currently lack effective therapies.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with ultra-rare neurological disorders, particularly those with a genetic basis.

Not a fit: Patients with common neurological disorders or those without a genetic component may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new gene therapies for patients suffering from ultra-rare neurological disorders.

How similar studies have performed: Previous research has shown promise in gene therapy approaches for rare diseases, indicating potential for success in this novel consortium effort.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.