A centralized hub for advanced immunological analysis
Official title: Molecular Immunology Core
Funded at Massachusetts General Hospital · NIH-11035225 · Data updated 2026-11-12
This study is working on a new center that will help scientists better understand how the immune system reacts to lung transplants, which could lead to better outcomes for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | March 23, 2023 |
| Project end | February 29, 2028 |
| Funding year | 2025 |
| Award (this year) | $659,958 |
| NIH project number | 5U19AI174967-03 |
| Project ID | NIH-11035225 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing lung transplantation or those with conditions requiring advanced immunological analysis.
✕Less likely to help
Patients who are not undergoing transplantation or do not have immune-related conditions may not benefit from this research.
What this research studies
This research focuses on creating a centralized facility that will enhance the analysis of biological samples related to immune responses, particularly in the context of lung transplant tolerance. It will streamline various assays and procedures to ensure consistency and best practices across multiple projects. The facility will consist of several specialized cores that will work together to improve the efficiency and rigor of experiments aimed at understanding how to achieve tolerance in lung transplants. Patients may benefit from improved transplant outcomes through better understanding and management of immune responses.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for achieving tolerance in lung transplants, potentially reducing the need for lifelong immunosuppression.
How similar studies have gone: Previous research in immunological analysis and transplant tolerance has shown promising results, indicating that this approach could build on established findings.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Kean, Leslie S — Massachusetts General Hospital
- Study coordinator: Kean, Leslie S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.