A center for advanced imaging techniques to visualize biological samples.
The National Center for In-situ Tomographic Ultramicroscopy (NCITU)
This study is all about helping researchers learn how to prepare tiny biological samples for a special imaging technique called cryo-electron tomography, so they can see the structures inside cells better and understand how they work.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York Structural Biology Center NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10991155 on NIH RePORTER |
What this research studies
The National Center for In-situ Tomographic Ultramicroscopy (NCITU) aims to develop and provide access to advanced methods for preparing biological specimens for cryo-electron tomography (cryoET). This center will offer hands-on services and training to researchers at various skill levels, ensuring high-quality sample preparation for direct visualization of macromolecular structures in native cells. By utilizing cutting-edge techniques such as plunge freezing and cryo-light microscopy, NCITU will enhance the understanding of cellular organization and interactions. The center will also expand its cross-training programs to disseminate expertise in cryoET specimen preparation.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include researchers and scientists working in the fields of structural biology and cell biology who require advanced imaging techniques.
Not a fit: Patients not involved in research or those outside the scientific community may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the ability to visualize and understand complex biological structures at the molecular level.
How similar studies have performed: Other research in advanced imaging techniques has shown success in enhancing our understanding of biological processes, indicating that this approach has the potential for significant impact.
Where this research is happening
New York, United States
- New York Structural Biology Center — New York, United States (Active)
Researchers
- Principal investigator: Kieft, Jeffrey S — New York Structural Biology Center
- Study coordinator: Kieft, Jeffrey S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.