Macromolecule dynamics and NMR tools center for biomedicine
Official title: RM1 Center on Macromolecular Dynamics by NMR Spectroscopy at the New York Structural Biology Center (CoMD/NMR)
Funded at New York Structural Biology Center · NIH-11380667 · Data updated 2026-11-12
A program to make advanced NMR-based methods and analysis more accessible to researchers studying cancers and related biological processes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York Structural Biology Center NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 1, 2022 |
| Project end | May 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,570,521 |
| NIH project number | 5RM1GM145397-05 |
| Project ID | NIH-11380667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Investigators and clinicians studying cancers who could benefit from advanced NMR-based insights into macromolecular dynamics.
✕Less likely to help
Patients directly will not enroll in this grant; benefits come from accelerated research that can inform future treatments.
What this research studies
This grant supports a center that develops and shares cutting-edge NMR techniques to study how proteins and nucleic acids move and interact in cancer-related biology. It emphasizes spin relaxation methods and related computational tools to reveal dynamic behavior during ligand binding, allostery, catalysis, and folding. The center also provides access to a suite of NMR instruments and training so a wider range of scientists can apply these methods to biological questions. Through shared protocols, software, and instrumentation, patients’ understanding of how macromolecules behave in cancer could improve future therapies.
Why it matters
Potential benefit: If successful, this program could accelerate discovery of dynamic molecular mechanisms in cancer, potentially leading to new targets and therapies.
How similar studies have gone: Previous adoption of advanced NMR methods by researchers has enabled more detailed dynamic insights and the center aims to broaden this impact.
Where this research is happening
-
New York Structural Biology Center
New York, United States Active
Researchers
- Principal investigator: Palmer, Arthur G — New York Structural Biology Center
- Study coordinator: Palmer, Arthur G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.